Pathophysiology Leishmania falls in the category of an eukaryotic disease. It has two morphological forms. One form is Promastigote which is the morphological style in the formation of some protazoas, which have free anterior flagellum characteristics, found in the insect host. The other form is Amastigote which does not have flagella.
Leishmania infections can be placed into three different categories of an infection type.
Cutaneous Leishmaniasis: These infections usually appear on your skin as a skin reaction and are usually obvious to spot. It can take weeks to months from the source of infection to the appearance of it on your skin (ussually arms, legs, neck, or face). They are ulcer looking sores that can be painful or painless.
Mucocutaneous Leishmaniasis: This infections starts
at the source of the bite right away. They go through a passage to the metastasis into the mucous membrane and can become fatal. This infections happens once the cutaneous lesion has healed and will come back to strict up to many years later inoral and respiratory mucosal involvement, causing inflammation and mutilation of the nose, mouth, oropharynx, and trachea.
Visceral Leishmaniasis: This infection can cause fever, swelling of the liver and spleen, and anemia. This is the most fatal form because it occurs from the immunosuppression and secondary infections. Patients with this infection have also reported night sweats, weakness, and anorexia. This can also cause skin hyperpigmentation.
Pathophysiology Leishmania falls in the category of an eukaryotic disease. It has two morphological forms. One form is Promastigote which is the morphological style in the formation of some protazoas, which have free anterior flagellum characteristics, found in the insect host. The other form is Amastigote which does not have flagella.
Leishmania infections can be placed into three different categories of an infection type.
Cutaneous Leishmaniasis: These infections usually appear on your skin as a skin reaction and are usually obvious to spot. It can take weeks to months from the source of infection to the appearance of it on your skin (ussually arms, legs, neck, or face). They are ulcer looking sores that can be painful or painless.
Mucocutaneous Leishmaniasis: This infections starts
at the source of the bite right away. They go through a passage to the metastasis into the mucous membrane and can become fatal. This infections happens once the cutaneous lesion has healed and will come back to strict up to many years later inoral and respiratory mucosal involvement, causing inflammation and mutilation of the nose, mouth, oropharynx, and trachea.
Visceral Leishmaniasis: This infection can cause fever, swelling of the liver and spleen, and anemia. This is the most fatal form because it occurs from the immunosuppression and secondary infections. Patients with this infection have also reported night sweats, weakness, and anorexia. This can also cause skin hyperpigmentation.